Teresa Szczepińska PhD

Education

PhD studies, Nencki Institute of Experimental Biology, Warsaw, 2007-2012 PhD degree in biology in the scope of bioinformatics

MSc Bioinformatics, VU University, Amsterdam, 2007 Master degree in bioinformatics

Interfaculty Individual Studies in Mathematical and Natural Sciences, Warsaw University, 2002-2006

Bachelor's degree in biotechnology in the scope of molecular biology, 2005

Research and Work Experience

• 2022-10 - present - CEZAMAT, Warsaw University of Technology. Head of the Bioinformatics and Genome Structure Laboratory
• 2020 Jul – 2022-09 - CEZAMAT, Warsaw University of Technology. Postdoc adviced by Dariusz Plewczyński
• 2018 Oct - 2020 Sep - CeNT, University of Warsaw. Postodc adviced by Dariusz Plewczyński
• 2019 Feb - 2019 June - MDC, Berlin. Internship in Ana Pombo Laboratory, extended to collaboration
• 2017 Aug - 2018 Aug - Parental leave
• 2015 Oct - 2017 Aug - CeNT, University of Warsaw. Postodc adviced by Dariusz Plewczyński
• 2015 Feb - 2015 Sep - Parental leave
• 2012 Oct - 2015 Jan - IBB PAS. Postdoc, advised by Andrzej Dziembowski
• 2007 Oct - 2012 Sep - Nencki Institute, PAS. PhD Student advised by Krzysztof Pawłowski
• 2011 Jan - 2011 Mar - UTMB, Galveston. Internship in Małgorzata Rowicka-Kudlicka Laboratory
• 2009 Feb - Karolinska Institute, Stockholm. Internship in Rolf Ohlsson Laboratory

Bioinformatics. Chromatin 3D structure.

• ‘In vitro immune evaluation of adenoviral vector-based platform for infectious diseases.’ Baran J, Kuryk Ł, Szczepińska T, Łaźniewski M, Garofalo M, Mazurkiewicz-Pisarek A, Mikiewicz D, Mazurkiewicz A, Trzaskowski M, Wieczorek M, Pancer K, Hallmann E, Brydak L, Plewczynski D, Ciach T, Mierzejewska J, Staniszewska M. BioTechnologia (Pozn). 2023
• ‘Novel combinatorial therapy of oncolytic adenovirus AdV5/3-D24-ICOSL-CD40L with anti PD-1 exhibits enhanced anti-cancer efficacy through promotion of intratumoral T-cell infiltration and modulation of tumour microenvironment in mesothelioma mouse model.’ Garofalo M, Wieczorek M, Anders I, Staniszewska M, Lazniewski M, Prygiel M, Zasada AA, Szczepińska T, Plewczynski D, Salmaso S, Caliceti P, Cerullo V, Alemany R, Rinner B, Pancer K, Kuryk L. Front Oncol. 2023
• ‘Multi-scale phase separation by explosive percolation with single-chromatin loop resolution.’ Sengupta K, Denkiewicz M, Chiliński M, Szczepińska T, Mollah AF, Korsak S, D'Souza R, Ruan Y, Plewczynski D. Comput Struct Biotechnol J. 2022
• ‘Genomic Marks Associated with Chromatin Compartments in the CTCF, RNAPII Loop and Genomic Windows.’ Szczepińska T, Mollah AF, Plewczynski D. Int J Mol Sci. 2021
• ’Intermingling of chromosome territories’ Szczepinska T, Rusek AM, Plewczynski DM, Genes, Chromosomes & Cancer (GCC) special issue on ’The 3D Nuclear Architecture of the Genome’. 2019 Jul;58(7):500-506
• ’The structural variability of the influenza A hemagglutinin receptor-binding site.’ Lazniewski M,Dawson WK, Szczepinska T, Plewczynski DM. Brief Funct Genomics. 2017 Dec 13.
• ’3DFlu: database of sequence and structural variability of the influenza hemagglutinin at populaion scale.’ Mazzocco G, Lazniewski M, Migdał P, Szczepińska T, Radomski JP, Plewczynski DM. Database (Oxford). 2016 Oct 2;2016
• ’DIS3 shapes the RNA polymerase II transcriptome in humans by degrading a variety of unwanted transcripts’ Szczepinska T, Kalisiak K, Tomecki R, Labno A, Borowski LS, Adamska D, Kosinska J, Dziembowski A Genome Res. 2015 Nov;25(11):1622-33.
• ’Probabilistic approach to predict substrate specificity of methyltransferases’ Szczepinska T, Kutner J, Kopczynski M, Pawlowski K, Kudlicki A, Dziembowski A, Ginalski K, Rowicka M PLoS Comput Biol. 2014 Mar 20;10(3)
• ’Genomic positions of co-expressed genes: Echoes of chromosome organisation in gene expression data.’ Szczepinska T, Pawlowski K BMC Res Notes. 2013 Jun 13;6:229
• ’Novel higher-order epigenetic regulation of the Bdnf gene upon seizures.’ Walczak A, Szczepankiewicz AA, Ruszczycki B, Magalska A, Zamlynska K, Dzwonek J, Wilczek E, Zybura-Broda K, Rylski M, Malinowska M, Dabrowski M, Szczepinska T, Pawlowski K, Pyskaty M, Wlodarczyk J, Szczerbal I, Switonski M, Cremer M, Wilczynski GM. J Neurosci. 2013 Feb 6;33(6)
• ’A novel protein kinase-like domain in a selenoprotein, widespread in the tree of life.’ Dudkiewicz M, Szczepinska T, Grynberg M, Pawlowski K. PLoS One. 2012;7(2):e32138. Epub 2012 Feb 16.
• ’A widespread peroxiredoxin-like domain present in tumor suppression- and progression-implicated proteins.’, Pawlowski K, Muszewska A, Lenart A, Szczepinska T, Godzik A, Grynberg M. BMC Genomics.

• Warsaw University of Technology Biomedical Engineering Discipline grant 2023
• Warsaw University of Technology IDUB BIOTECHMED-2 grant in 2020
• National Science Centre MINIATURA grant in 2019
• Award of the Division II of Biological and Agricultural Sciences of the Polish Academy of Sciences for the Scientific Team for a series of works entitled ’Role of ribonucleases in the regulation of degradation, treatment of RNA quality control in the nucleus and cytoplasm of human cells’ in 2017
• CeNT DSM grant in 2016
• Polish Genetic Society Award for the best publication in human genetics in 2015